Cellulite, also known as lipodystrophy or edematous-fibrosclerotic panniculopathy is a selective and organized subcutaneous accumulation of adipose tissue:

Selective, because it consists of fat deposits
Organized, as these deposits are grouped into lobules

The adipose tissue

The adipose tissue is made up of cells called adipocytes or lipocytes, of ovoid shape, with nucleus located in the periphery, since triglycerides and complex lipids (fats) prevail inside the cell.
The adipocytes are found almost in mutual contact with each other and are enclosed between connective tissue walls positioned from the surface in depth, therefore perpendicular to the skin.

Main functions of adipose tissue

- Trophic function: energy reservoir, because depending on the time, it stores (after meals) or releases (fasting, interval between meals, breastfeeding, physical activity) free fatty acids.
- Thermal insulation: reduces heat loss.
- Adjustment and storage: regulates the metabolism of triglycerides, glucose, fatty acids (processes of lipogenesis and lipolysis) and cholesterol.
- Mechanical or protective function: Fat is a good shock absorber for light trauma.
- Plastic or modeling function: it determines some body shapes (breasts, hips, buttocks, abdomen) carrying out a secondary sexual character.

Mechanism of action of cellulite

There are 2 types of cellulite:
- Hypertrophic: increase in the volume of adipocytes due to triglycerides
- Hyperplasty: increased number of adipocytes, often hereditary

Cellulite begins with an accumulation of fat: if the demand for energy exceeds the immediately available supplies (sugars), the triglycerides stored in the adipocytes are destructured, releasing the necessary energy. If, on the other hand, the diet is too rich in fats and sugars compared to daily needs, the excess is stored in the form of triglycerides by the adipocytes.
Between these cells, blood vessels, arterial and venous vessels and lymphatic vessels that supply nourishment to the epidermis branch out towards the upper layers. An increase in the number or volume of adipocytes involves compression of the vessels, consequently:
- At the level of the blood vessels, the flow slows down, the tissues are less oxygenated and the nourishment up to the epidermis is limited> "orange peel" skin appearance. Furthermore, since the vessels are made up of valves that push the blood upwards, with the increase in the volume of the adipocytes, they undergo a constriction, causing them to reflux, with consequent flattening of the walls, up to the formation of varicose veins.
- At the level of the lymphatic vessels, the pressure exerted on them slows down the elimination of toxins and increases the infiltration of water into the underlying tissues, as there will be lymph carried by the capillaries which will become interstitial lymph, then edema and then it will bind to the adipocytes becoming cellulite until the formation of "islets" perceptible to the touch.
- In addition, the formation of a hardening around the adipose nodules (sclerotic fibers), will slow down cellular exchanges, prevent the penetration of the active anti-fat ingredients and lead to an increase in the thickness of the epidermis and dermis, even if to a lesser extent, as well as to the hypodermic one.

Stages of cellulite

1st stage: alteration of the normal state of fats and increase in the permeability of capillaries and lymphatic ducts; consequently, instead of letting regulated quantities of nutrients pass, these, together with the blood plasma, accumulate between the interstices of the adipocytes, causing considerable tension (edema) and a progressive swelling of the adipose tissue.
The skin is shiny with a characteristic "orange peel" appearance; to the touch, hot, dry and rough. This first stage, especially in puberty, is the easiest to treat and the application of the Alkemilla 90-60-90 Cream guarantees excellent results.
2nd stage: the compressed cells, no longer continuously emptied and filled, begin to aggregate in small groups; small fibers (fibrils) of support material (collagen) are formed to hold them together and connect them.
The substances capable of binding intracellular water, called glycosaminoglycans, formed by proteins and sugars, increase. The space available for blood circulation is reduced and blood flow slows down (haemostasis).
This stage is characterized by a rubbery texture and the "orange peel" appearance is more evident.
3rd stage: it is characterized by the isolation of fat cells from nourishment and mobilization materials; the waste materials cannot be eliminated and the aggregated cells compact into micro nodules measuring several millimeters, surrounded by layers (and not just more fibers) of hardened fibrous materials.
There is a gelatinous tissue that slips under the skin, seems to change according to the posture assumed and wobbles with walking. There may be superficial circulatory alterations (dilated capillaries, hematomas, reddish spots, i.e. telangiectasias) and deep (swollen legs).
The skin is cold, sagging, with atrophic muscle masses.
4th stage: Nodules become larger (up to twenty millimeters) and exert pressure on the nerves. At the slightest contact, the skin will be sensitive or even sore.
The altered blood and lymphatic circulation and the change in the balance of the storage and consumption of fats, cause changes to the structure of the subcutaneous adipose tissue, which in turn induces changes to the surrounding matrix of filling and structural materials.

Causes of Cellulite


- Inheritance
- Adolescence: period characterized by numerous psychophysical mutations and neuroendocrine revolution which often cause the onset of cellulite.
- Constipation or constipation: an accumulation of faeces, produced over time, leads to a reabsorption of waste, which through the walls of the intestine, creates a real general intoxication of the organ itself; all this also has a negative effect on the skin connective, increasing the amount of toxins contained in it.
- Alterations in hormonal balance: often the predominant cause, are the hormones estrogen, as they cause water retention.


- Stress: continuous anxious states, lead to a greater production of adrenaline (vasoconstrictor effect), a hormone which, if in excess, causes damage to blood vessels and consequently damages circulation.
- Pregnancy: by altering the metabolic processes and hormonal balance, it leads to a defective circulation, especially in the legs which must also support greater weight.
- Birth control pill: does nothing but reproduce a state of pregnancy with the consequences that it entails.

Bad habits

- Incorrect feeding: it is necessary to respect the balance of the various foods between the parameters of carbohydrates, proteins and fibers.
- Abuse of smoking and alcohol: highly toxic to the body.
- Salt abuse: promotes water retention.
- Too tight clothing: busts, jeans, belts, stockings, etc. they can hinder blood circulation.
- Too violent sports: they can give rise to cellulite, if not aggravate it, due to an overproduction of lactic acid in the muscles if subjected to excessive strain. Adequate exercise, on the other hand, and therefore good muscle functioning, favors the vascularization of adipose tissue and therefore also metabolic efficiency.

Difference between cellulite and localized adiposity

Localized adiposity is an increase in the number and volume of adipocytes, i.e. a total increase in adipose tissue.
Cellulite, on the other hand, affects all elements of the adipose tissue (vessels, nerves, fibers, adiposity, fundamental substance).
This explains why following even a drastic diet, fat melts, while cellulite never disappears spontaneously.

Alkemilla 90-60-90 is ideal for combating adiposity and cellulite.

Differences between man and woman

Women are more involved in the phenomenon of cellulite than men due to the different distribution of body fat due to the ovarian hormones estrogen> they are mainly ginoids (but also androids), so cellulite is localized especially in the lower part of the body.
The women they also have more abundant subcutaneous adipose tissue than the male one.
Furthermore, due to the different structuring of the connective tissue (with rectangular and discontinuous packing, immediately under the dermis, with larger nodules of fat), the woman "gets tired" as it accumulates laterally (this also happens to contain the weight of pregnancy) .
The men they are androids, so cellulite is localized in the upper part of the body (abdominal band, hips, chest, but also neck and shoulder). The connective is diagonally packed.

90-60-90 Alkemilla is ideal for both men and women.

90-60-90 reasons to choose Alkemilla cream

Indispensable in the strategy of attacking cellulite and adiposity:

Vasodilating and warming action, thanks to local hyperemia, it mobilizes both fats and water retained by the adipose panniculus and promotes their elimination by activating blood circulation.
Improves blood and lymphatic circulation, stimulates cellular exchanges and oxygenation.
Helps eliminate waste.
Drains liquids and waste substances between the interstices of the cells.
It nourishes the tissues restoring water balance to dehydrated areas; the skin returns luminous, regains firmness and tone.
Stimulating effect at the level of microcirculation: it stimulates the passage of lymph into the lymphatic vessels, increasing the intrinsic capacity that each lymphatic vessel has to contract; the arterial capillaries, freed from excess interstitial fluid, allow the tissues to better oxygenate.